职 务：

职 称：

讲师

评聘时间：

2020-10

所在系：

环境科学

专业：

环境科学

主要研究方向：

环境毒理学、功能纳米材料

主讲课程：

环境生物学、环境系统分析、环境毒理与健康风险

联系电话：

电子邮箱：

qhqian@usts.edu.cn

个人简介：

主要从事环境毒理学和功能纳米材料的研发相关研究，目前已在Journal of Hazardous Materials、Matter、Small、Biomaterials等学术期刊上发表学术论文10余篇，申请国家发明专利2项。参与国家自然科学基金重大项目1项，国家自然科学基金面上项目1项。

学习经历：

2014.09-2020.06 上海交通大学 直博

2010.09-2014.06 南京师范大学 学士

个人荣誉：

2021年江苏省“双创博士”

社会兼职：

论文论著：

1. Diao, W.; Yan, J.; Wang, X.; Qian, Q.^*; Wang, H., Mechanisms regarding cardiac toxicity triggered by up-regulation of miR-144 in larval zebrafish upon exposure to triclosan.Journal of Hazardous Materials 2023, 443. 130297. (IF: 14.2)

2. Wang, Y.; Song, J.; Wang, X.; Qian, Q.^*; Wang, H., Study on the toxic-mechanism of triclosan chronic exposure to zebrafish (Danio rerio) based on gut-brain axis.Science of the Total Environment 2022, 844, 156936. (IF: 10.6)

3. Qian, Q.; Wang, D.; Shi, L.; Zhang, Z.; Qian, J.; Shen, J.; Yu, C.; Zhu, X., A pure molecular drug hydrogel for post-surgical cancer treatment.Biomaterials 2021, 265, 120403. (IF: 15.3)

4. Qian, Q.; Zhu, L.; Zhu, X.; Sun, M.; Yan, D., Drug-polymer hybrid macromolecular engineering: Degradable PEG integrated by platinum(IV) for cancer therapy.Matter 2019, 1, 1618-1630. (IF: 19.97)

5. Qian, Q.; Shi, L.; Gao, X.; Ma, Y.; Yang, J.; Zhang, Z.; Qian, J.; Zhu, X., A paclitaxel-based mucoadhesive nanogel with multivalent interactions for cervical cancer therapy.Small 2019, 15, 1903208. (IF: 15.2)

6. Qian, Q.; Song, J.; Chen, C.; Pu, Q.; Liu, X.; Wang, H., Recent advances in hydrogels for preventing tumor recurrence.Biomaterials Science 2023, DOI:10.1039/D3BM00003F. (IF: 7.6)

7. Diao, W.; Qian, Q.(共同一作); Sheng, G.; He, A.; Yan, J.; Dahlgren, R. A.; Wang, X.; Wang, H., Triclosan targets miR-144 abnormal expression to induce neurodevelopmental toxicity mediated by activating PKC/MAPK signaling pathway.Journal of Hazardous Materials 2022, 431, 128560.(IF: 14.2)

8. Sun, M.; Qian, Q.(共同一作); Shi, L.; Xu, L.; Liu, Q.; Zhou, L.; Zhu, X.; Yue, J.-M.; Yan, D., Amphiphilic drug-drug conjugate for cancer therapy with combination of chemotherapeutic and antiangiogenesis drugs.Science China-Chemistry 2020, 63, 35-41. (IF: 10.2)

9. Xu, J.; Qian, Q.; Xia, M.; Wang, X.; Wang, H., Trichlorocarban induces developmental and immune toxicity to zebrafish (Danio rerio) by targeting TLR4/MyD88/NF-kappa B signaling pathway.Environmental Pollution 2021, 273, 116479. (IF: 10.0)

10. Zhu, L.; Guo, Y.; Qian, Q.; Yan, D.; Li, Y.; Zhu, X.; Zhang, C., Carrier-free delivery of precise drug-chemogene conjugates for synergistic treatment of drug-resistant cancer.Angewandte Chemie-International Edition 2020, 59, 17944-17950. (IF: 16.8)

11. Zhao, C.; Xie, R.; Qian, Q.; Yan, J.; Wang, H.; Wang, X., Triclosan induced zebrafish immunotoxicity by targeting miR-19a and its gene socs3b to activate IL-6/STAT3 signaling pathway.Science of the Total Environment 2022, 815, 152916. (IF: 10.8)

12. Sun, L.; Gao, M.; Qian, Q.; Guo, Z.; Zhu, P.; Wang, X.; Wang, H., Triclosan-induced abnormal expression of miR-30b regulates fto-mediated m(6)A methylation level to cause lipid metabolism disorder in zebrafish.Science of the Total Environment 2021, 770, 145285. (IF: 10.8)

13. Xia, M.; Wang, X.; Xu, J.; Qian, Q.; Gao, M.; Wang, H., Tris (1-chloro-2-propyl) phosphate exposure to zebrafish causes neurodevelopmental toxicity and abnormal locomotor behavior.Science of the Total Environment 2021, 758, 143694. (IF: 10.8)

专利：

1. 一种多价键纳米凝胶及其在宫颈癌原位治疗药物中的用途, 2018-4-11, ZL201810321270.0，授权

2. 一种雷替曲塞水凝胶及其制备方法和用途, 2018-4-19, ZL201810355905.9，授权

承担项目：

江苏省双创博士，15万，2021，主持，在研

获奖成果：